PME 5103-0

Brief

This course is designed for graduate students who have taken fundamental courses in Microfluidics (such as PME 5170 Thermo-fluidics in Bio-MEMS). It will cover advanced topics in microfluidics, including critical microfluidic devices and integrated microfluidic systems. Their biomedical applications for DNA, RNA, proteins, and cells will be extensively investigated.

Description

Course keywords: 奈微流體生醫系統 、微幫浦、 微混合器 、細胞晶片、 組織晶片 中文名稱: 進階微流體系統 英文名稱：Advanced Microfluidic Systems 授課老師：李國賓 學 分 數：3學分 擬開課年級:碩博 This course is designed for graduate students who have taken fundamental courses in Microfluidics (such as PME 5170 Thermo-fluidics in Bio-MEMS). It will cover advanced topics in microfluidics, including critical microfluidic devices and integrated microfluidic systems. Their biomedical applications for DNA, RNA, proteins, and cells will be extensively investigated. 課程大綱: 1. Introduction to microfluidics 2. Review of microfabrication technologies for microfluidics- silicon- based and non-silicon-based techniques (reading assignment) 3. Case study on micro fabrication of simple fluidic devices---micro channel, cavity, diaphragm etc. 4. Micro flow sensors (reading assignment) (a) Temperature sensors (b) Pressure sensors (c) Shear stress sensors (d) Flow velocity sensors 5. Microfluidic devices (a) Micro pumps (b) Micro valves (c) Micro mixers (d) Micro nozzles (e) Micro injectors (f) Micro flow switches (g) Micro bio-reactors (h) Micro separators (micro capillary electrophoresis and micro-filters) 6. Microfluidic systems (a) flow cytometer (b) protein chips (c) DNA chips (d) cell chips 7. Special topics for microfluidic systems References: 1. “Fundamental and applications of microfluidics” by Nam-Trung Nguyen and Steven T. Wereley, 2002 2. “Microfluidic Technology and Applications (Microtechnologies and Microsystems Series) “ by Michael Koch, et al., 2000. 3. "Microsensor - Principles and Applications", by J. W. Gardner, Wiley, 1996. 4. " Semiconductor Sensors", by S. M. Sze, John Wiley & Sons, Inc. , 1994 5. " Micromechanics and MEMS-classic and seminal papers to 1990", edited by W. S. Trimmer, IEEE press, 1996. 6. "Fundamental of microfabrication", by Marc Madou, CRC press, New York, 1997. 7. "Micromachined Transducers- Sourcebook", by G. T. A. Kovacs, WCB/McGraw, 1998. Grading policy: Homework 30 % Midterm 40 % Final project & final presentation 30 % ** Collaboration is highly encouraged in this course. You have to form a team with 2-3 partners to finish your final project. Office hours: Friday 16:00 pm –17:00 pm Office: Rm. 608, Department of Power Mechanical Engineering, NTHU Tel. No.: ext 33765 E-mail: gwobin@pme.nthu.edu.tw Important deadlines: 1. First draft of proposal for your final paper: 5th week. 2. Midterm exam: 10th ~ 11th week 3. Final presentation: 17th week. 4. Final paper: 18th week. Teaching Assistant: to be announced. 有條件開放，請註明如何使用生成式AI於課程產出 (Conditionally open; please specify how generative AI will be used in course output)

Timetable

Scores

Average Percentage 80.86

Std. Deviation 5.99

Remarks

動機系碩士班生醫系統組課程

Restrictions

Compulsory

Elective

Cross Discipline

First Specialization

Second Specialization