LSBT 5762-0

Brief

疫苗與免疫科學課程內容主要講述先天性免疫,T細胞與體液免疫系統,免疫動態系統與黏膜免疫理,同時就疫苗發展與佐劑 的應用，抗原特性與新疫苗技術發展如活毒疫苗，次單元與類病毒顆粒疫苗，病毒與細菌載體疫苗與基因疫苗加以介紹． 同時除了針對預防性疫苗外也包括新發展的治療性疫苗應用於癌症,異體移植與自體免疫疾病, …等．

Description

Course keywords: 疫苗 佐劑 抗原 先天性免疫 體液免疫 細胞免疫 一、課程說明(Course Description) The course contains the principles of innate immunity, cellular and humoral adaptive immunity, dynamic of adaptive immune system and mucosal immunity, and the applications to vaccine development such as adjuvants, antigen character and epitope analysis, and the new generations of vaccine development such as viral and bacterial vector vaccines, recombinant protein vaccines, DNA vaccines as well as new therapeutic vaccines against neoplasm, loss individuality, and organ or tissue damages. 疫苗與免疫科學課程內容主要講述先天性免疫,T細胞與體液免疫系統,免疫動態系統與黏膜免 疫理,同時就疫苗發展與佐劑的應用，抗原特性與新疫苗技術發展如活毒疫苗，次單元與類病毒顆 粒疫苗，病毒與細菌載體疫苗與DNA疫苗加以介紹．同時除了針對預防性疫苗外也包括新發展的治 療性疫苗應用於癌症,異體移植與自體免疫疾病, …等． 二、指定用書(Text Books) Janeway's Immunobiology, 10th edition, Kenneth Murphy, Casey Weaver, and Leslie Berg, 2022 Chapter 3 The induced response of innate immunity Chapter 6 Antigen presentation to T lymphocytes Chapter 9 T cell-mediated immunity Chapter 10 The humoral immune response Chapter 11 Integrated dynamics of innate and adaptive immunity Chapter 12 The mucosal immune system 三、參考書籍(References) Vaccinology: principle and practice, Morrow, Sheikh, Schmidt, Davies, Wiley- Blackwell 2012 Immunopotentiators in modern vaccines, Virgil Schijns and Derek OHagan, second edition, Academic Press 2017 Part 1 Introduction Part 2 Principles of vaccine design Part 3 Antigen discovery Part 4 Antigen engineering Part 5 Delivery systems Part 6 Regulatory Consideration Part 7 Evaluating vaccine efficacy Part 8 Implementing immunizations/therapies 四、教學方式(Teaching Method) English lectures 五、教學進度(Syllabus) Chapter 3 The Induced Response of Innate Immunity Chapter 6 Antigen Presentation to T lymphocytes Chapter 9 T cell-mediated immunity Chapter 10 The humoral immune response Chapter 11 Integrated dynamics aof innate and adaptive immunity Chapter 12 The mucosal immune system 六、成績考核(Evaluation) Mid-term and final exams 七、可連結之網頁位址

Timetable

Scores

Average Percentage 87.36

Std. Deviation 2.64

Remarks

16週

Restrictions

Compulsory

Elective

Cross Discipline

First Specialization

Second Specialization