CHE 5900-0

Brief

此課程將會介紹基本生物學, 分子生物學, 基因工程,、蛋白質表現系統、轉植基因動物、疫苗工程、基因治療及免疫療法等方 面之應用。期末將以期末報告代替考試，期許學生能整合上課所學知識，以口頭及簡報呈現完整之報告。 This course covers fundamental cell biology, molecular biology, genetic engineering as well as applications in protein ex<x>pression, vaccine engineering, gene therapy and immunotherapy, etc.

Description

Course keywords: 分子生物學, 基因工程, 蛋白質表現系統、疫苗工程、基因治療及免疫療法, molecular biology, genetic engineering, protein ex<x>pression system, vaccine engineering, gene therapy and immunotherapy 一、課程說明(Course Description) 此課程將會介紹基本生物學, 分子生物學, 基因工程,、蛋白質表現系統、轉植基因動物、疫苗工程、 基因治療及免疫療法等方面之應用 This course covers fundamental cell biology, molecular biology, genetic engineering as well as applications in protein expression, vaccine engineering, gene therapy and immunotherapy, etc. 二、指定用書(Text Books) Glick BR, Pasternak JJ and Patten, C.L. (2010) Molecular Biotechnology: Principles and Applications of Recombinant DNA. 4th ed. ASM Press, Washington, D.C. 三、參考書籍(References) 1.Shuler ML and Kargi F. (1992) Bioprocess Engineering: Basic Concepts. Prentice Hall International, London. 2.Watson, JD, Gilman, M, Witkowski, J, Zoller, M. (1992) Recombinant DNA. 2nd Ed. W.H. Freeman and Co., New York. 3.Freshney, RI (2000) Culture of animal cells, a manual of basic technique. 4th Ed. Wiley-Liss, New York. 4.Ausubel et al (1999) Short protocols in molecular biology. 4th Ed. John Wiley and Sons, New York. 四、教學方式(Teaching Method) 教師授課及學生報告為主 五、教學進度(Syllabus) Basics Chap 1 Overview of Cellular Biology (19) Chap 2 DNA, RNA, Transcription and Translation (24) Chap 3 Recombinant DNA Technology (19) Chap 4 Chemical Synthesis, Sequencing and Amplification of DNA (14) Chap 5 Manipulation of Gene expression in Procaryotes (11) Chap 6 Manipulation of Gene expression in Eucaryotes (13) Applications: Chap 7 Vaccines (18) Chap 8 Human Gene Therapy (26) Chap 9 Immunotherapy (7) Chap 10 Genome Editing and Manipulation (10) 六、成績考核(Evaluation) Mid-term exam: 50 % Final presentation: 40% Course participation (including quiz): 10% 七、可連結之網頁位址 http://www2.che.nthu.edu.tw/~biohu/Main_zh.htm

Timetable

Scores

Average Percentage 87.18

Std. Deviation 6.09

Remarks

Restrictions

Compulsory

Elective

Cross Discipline

First Specialization

Second Specialization