BME 5050-0

Brief

This course is designed to acquaint students with the forefront technologies and significant challenges within cell-ba<x>sed regenerative therapies. Alongside lectures, weekly paper discussion sessions will foster deeper engagement. Moreover, students are encouraged to present their weekly experimental findings in the realm of cell therapy.

Description

Course keywords: 再生醫學, 細胞治療, 幹細胞, 細胞遞送, 胞外囊泡, regenerative medicine, cell therapy, stem cell, cell delivery, extracellular vesicle References 1. Dwaine F. Emerich and Gorka Orive, Cell Therapy: Current status and future directions, Humana Press, New York, 2018 (ISBN 978-3-319-57153-9) 2. Journal papers Teaching Method Lectures, discussion, students’ oral presentation Syllabus 1. Course introduction 2. Current status and challenges of cell-based regenerative therapies 3. Molecular mechanisms of cell therapy-induced regeneration 4. Strategies for tracing the transplanted cells 5. Animal models for evaluating the efficacy of cell therapies 6. Biomaterials for cell therapy (I): Cell encapsulation 7. Biomaterials for cell therapy (II): Scalable cell production 8. Midterm exam 9. Cell-derived products as therapeutics (I): Extracellular vesicles 10. Cell-derived products as therapeutics (II): Mitochondria 11. Regulations for cell therapy 12. GTP/GMP Cell Manufacturing Facilities 13. Cell-based therapies for cardiovascular diseases 14. Cell-based therapies for neurodegenerative diseases 15. Cell-based therapies for musculoskeletal disorders 16. Cell-based therapies for diabetes mellitus 17. Term project presentation 18. Final exam Evaluation Midterm exam: 25% Final exam: 25% Term project: 20% Class discussion: 20% Attendance: 10% Declaration for Student Use of AI: 本課程無涉及AI使用 Not applicable

Timetable

Scores

Average GPA 4.3

Std. Deviation 0

Remarks

(1)需與授課教師討論後加簽選課Requiring application in order to enroll in the course. (2.)16週課程

Restrictions

Compulsory

Elective

Cross Discipline

First Specialization

Second Specialization