LSBT 5456-0

Brief

This course aims to provide the update-to-date knowledge related to the regulatory mechanism of ion channels, particularly related to development of diseases. Students will learn how ion channels regulate different physiological and pathological conditions, and develop their idea and critical thinking about how to target ion channels for future therapeutic strategies.

Description

Course keywords: ion channel, Pannexin, immune disorder, inflammation, ATP, cardiovascular diseases 指定用書(Text Books) & 參考書籍(References) 1. Bertil Hille, Ion Channels of Excitable Membranes, Third Edition. 2. Areles Molleman, Patch Clamping – An Introductory Guide to Patch Clamp Electrophysiology 3. Recently published high-profile research papers 教學方式(Teaching Method) Student presentations and group discussion 教學進度(Syllabus) The following topics will be covered: 1. Introduction of ion channels and their functions and regulation 2. Biophysical properties of ion channels 3. Activation mechanisms and inhibitors of ion channels 4. Regulation of ion channels by receptor-mediated signaling pathways 5. Methodologies and techniques for studying ion channels. 6. Ion channels in immune systems. 7. Ion channels in cardiovascular systems. 成績考核(Evaluation) Attendance (30%),presentation (40%), and discussion (30%)

Timetable

Scores

Average Percentage 87.67

Std. Deviation 2.05

Remarks

需與授課教師討論後加簽選課

Restrictions

Compulsory

Elective

Cross Discipline

First Specialization

Second Specialization