LSBS 5650-0

Brief

In this course, we will introduce essential servers, databa<x>se and online tools in Bioinformatics such as NCBI Gene Bank, Protein Data Bank (PDB), ExPASy, KEGG et al. We will also conduct hand-on exercises in functional genomics and protein analyses.

Description

Course keywords: Biological Databa<x>se, DNA sequence analysis, Protein sequence analysis, Protein structure analysis, Protein interaction This course is offered in English. 本課程採英文授課. (如果沒有外籍生選課，將改以中文上課) Parts of the contents require basic knowledge in Biochemistry. 部分內容需具有生科系大二生化基礎 一、課程說明(Course Description) In this course, we will introduce essential Servers, Database and Online tools in Bioinformatics. We will also conduct hand-on exercises in functional genomics and protein analyses. 本課程兼重學理與實作，藉由習題與範例，使學員能熟悉網路上各種生物資訊之取得及工具應 用，並針對各種常用生物資料庫作概略性的介紹，包括 NCBI, Protein Data Bank (PDB)、 KEGG、ExPasy 等生物資料庫。 課程中將連線上網，實際操作、演練各種輔助軟體 (Browser, viewer, molecular displayer...)。 二、參考書籍(References) 1. Bioinformatics: a practical guide to the analysis of genes and proteins Third Edition -- Gene Module 三、教學方式(Teaching Method) Lectures and hand-on training will be offered in Life Science computer room. 在電腦教室上課，課堂講解示範與學生實地操做並行。 四、暫定教學進度(Tentative Syllabus) 1. Introduction to Bioinformatics: 2. Information retrieval from biological database 3. DNA Database - GeneBank 4. DNA Sequence Analysis 5. Protein Sequence Database - SwissProt 6. Protein Sequence Analysis 7. Protein Structure Database - PDB 8. Protein Structure Analysis 9. Protein Structure Comparison 10. Protein Structure Modelling 11. Protein Docking and Drug Design 13. KEGG 五、成績考核(Evaluation) 1. Grading policy - Homeworks/practices 50% / Exam. 30% / Final Projects 20% 2. 5% credit will be deducted for late homework. 3. Do not be late for the class. Two counts of late arrival will be marked as 1 absence (10% credit deduction for the final score.) Three absences will result in a "F" of the final grade. 遲到兩次以曠課一次論，曠課一次扣總成績十分，曠課三次以不及格論。 六、可連結之網頁位址 (links) NTHU E-Learning System: http://ilms.nthu.edu.tw/ NTHU LS Alpha server: http://alpha.life.nthu.edu.tw/

Timetable

Scores

Average GPA 3.53

Std. Deviation 0.56

Remarks

Restrictions

Compulsory

Elective

Cross Discipline

First Specialization

Second Specialization