LSBS 5252-0

Brief

The ability to repair tissue injuries is essential for survival and is a prerequisite for all invasive medical intervention. It has been shown that wound healing and cancer me<x>tastasis share common early signaling pathways that have led to the hypothesis that tumors are “wounds that do not heal”. In fact, cancer progression and wound healing are influenced by many common factors, for example, regulators of angiogenesis and inflammation are instrumental in different types of oncological therapy and wound healing/regeneration. With a focus on current research projects in Prof. YJ Chuang;s lab, this special topics course begins with a systemic review of current topics in wound healing and cancer therapy, followed by general and then focused discussion of involved factors that are of interest.

Description

Course keywords: Thesis Project, Lab skills, Readings @@@ 需與老師討論後加簽。 一、課程說明 The ability to repair tissue injuries is essential for survival and is a prerequisite for all invasive medical intervention. It has been shown that wound healing and cancer metastasis share common early signaling pathways that have led to the hypothesis that tumors are “wounds that do not heal”. In fact, cancer progression and wound healing are influenced by many common factors, for example, regulators of angiogenesis and inflammation are instrumental in different types of oncological therapy and wound healing/regeneration. With a focus on current research projects in Prof. YJ Chuang;s lab, this special topics course begins with a systemic review of current topics in wound healing and cancer therapy, followed by general and then focused discussion of involved factors that are of interest. 二、指定用書 1. The link Between Inflammation and Cancer: Wounds that do not heal (Cancer Treatment and Research), Springer, 2005, by Angus G. Dalgleish and Burkhard Haefner 2. Tissue Repair and Fibrosis: The Role of the Myofibroblast (Current Topics in Pathology), Springer, 2012, by Alexis Desmouliere and Beatriz Tuchweber 三、參考書籍 選取自知名期刊 (i.e. Science, Nature, Cell, Proc. Natl. Acad. Sci. USA, Blood, Circulation Research…)之相關最新原始文獻 四、教學方式 講解、討論、辯證、報告 五、教學進度 每週深入探討、解析 1-2 篇學術論文與實驗數據 六、成績考核 課堂中參與討論 (50%)；專題報告 (50%) 七、講義位址 http:// NTHU iLMS：http://lms.nthu.edu.tw @@@ 需與老師討論後加簽。

Timetable

Scores

Average GPA 4

Std. Deviation 0

Remarks

需與授課教師討論後加簽選課

Restrictions

Compulsory

Elective

Cross Discipline

First Specialization

Second Specialization